Antipsychotics increase type 2 diabetes risk
Patients taking certain antipsychotics appear to be at increased risk of developing type 2 diabetes, BMJ Open reports.
Researchers analysed data collected from 262,982 people (aged between 40 and 60 years in 2006) who received metformin at any time until 2011. Of these, 24,493 received at least one antipsychotic.
The authors used metformin as a “proxy” for “clinically significant” type 2 diabetes that could not be modified by lifestyle changes. The authors could not allow for metformin’s other less common indications, such as polycystic ovary syndrome.
Patients dispensed a second-generation antipsychotic were 49 per cent more likely to start metformin compared with untreated controls.
Patients prescribed clozapine or olanzapine, which have a high risk of inducing weight gain, were 2.41 times more likely to start metformin. The analysis could not, however, allow for adherence.
Record my learning outcomes
Inspiring stories related to health, fitness and the pursuit of wellbeing
More like this
Learning update: Men's health and erection problems
Engaging with men about their health should be viewed as an opportunity for increased pharmacy intervention – especially in the area of erection problems.
6 Min Article
Fatigue, insomnia and anxiety are long term consequences of Covid-19
Study in The Lancet looks at Covid patients six months after discharge.
1 Min Article
Benzodiazepines prescribed more in deprived areas, study confirms
Researchers found prescribing rates were 45 per cent higher in the most deprived populations compared to the least.
1 Min Article
Update your knowledge of erection problems with key learning updates from recent research
4 Min Module
Advising customers of a unique formulation for a blocked and runny nose from colds
Understand the differences between topical medication for nasal symptoms of the common cold, and topical medication for ongoing nasal problems
25 Min Module