Research

Tramadol associated with higher mortality in OA

Tramadol is associated with significantly higher mortality than non-steroidal antiinflammatory drugs in people with osteoarthritis

Second-hand smoke raises risk of kidney disease

Exposure to second-hand smoke is associated with a greater risk of developing chronic kidney disease (CKD), say Korean researchers

New asthma treatment

The CHMP has approved dupilumab (Dupixent) as add-on maintenance treatment for some patients 12 years and older with severe asthma

HbA1c misses many cases of diabetes

“Our results indicated that the prevalence of diabetes and normal glucose tolerance defined solely by A1c is highly unreliable," said a researcher

ADHD treatments can trigger psychosis

About one in 660 adolescents and young adults receiving prescription stimulants for attention deficit hyperactivity disorder (ADHD) develop psychosis

MS drug improves survival

Beta-interferons produce “a significant survival advantage among people with relapsing-onset multiple sclerosis” (RRMS), according to a new study

New class of haemophilia A treatment

The European Commission recently approved emicizumab (Hemlibra) to prevent bleeding episodes in people with severe haemophilia A

Asthma rates falling

Researchers found that 6.52 per cent of the UK population had asthma in 2016 compared with 7.22 per cent in 2006

HCV: DAAs reduce deaths and cancer

Direct-acting antivirals (DAA) seem to reduce mortality and hepatocellular carcinoma in people with chronic hepatitis C

Antipsychotics increase type 2 diabetes risk

Patients taking certain antipsychotics appear to be at increased risk of developing type 2 diabetes, BMJ Open reports

‘Game changer’ for opioid dependence

Buvidal (buprenorphine prolonged release solution) allows weekly and monthly treatment of opioid dependence

Fluconazole should be avoided during pregnancy

Maternal exposure to just one dose of oral fluconazole during pregnancy may increase the risk of spontaneous abortion

No link between AEDs and dementia

The researchers did not identify a statistically significant association between AEDs and dementia

Vitamin D supplements help resistant TB

Vitamin D supplements accelerated clearance of multidrug-resistant pulmonary tuberculosis (TB), according to a new analysis

Conference call: ASHP updates on opioid crisis

Opioid over-prescribing, medical cannabis and digital health developments were some of the topics covered

The antidepressant gamble

A research team is asking community pharmacists to help develop a tool to personalise treatment for depression

High street teeth whitening kits can damage teeth, study shows

Non-hydrogen peroxide OTC teeth whitening kits can harm teeth by reducing hardness and damaging the tooth surface

E-cigarettes shown to be more effective than NRT

E-cigarettes are more effective than nicotine replacement therapy when combined with behavioural support

New diabetes drug available

A new once-weekly injectable glucagon-like peptide 1 receptor agonist (GLP-1 RA), is available for type 2 diabetes

Pharmacists could manage some emergency admissions

‘Potentially pharmacist-manageable conditions’ accounted for 4.3 per cent of A&E visits in a Canadian study

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