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Update on type 2 diabetes

This CPD module provides an overview of the recently updated NICE guideline on type 2 diabetes. It highlights key changes to the overall treatment strategy and the role of pharmacy teams in individualising and optimising care for people living with type 2 diabetes – especially those who are newly diagnosed.

After completing this module, you will be able to: 

  • Describe key changes in treatment recommendations for people with type 2 diabetes
  • Recognise the need for individualised care plans
  • Support people with type 2 diabetes to make decisions about therapy and optimal management
  • Liaise with other healthcare professionals and signpost people with type 2 diabetes to relevant sources of education and further support.  

Author: Josephine Fáladé, associate professor, UCL School of Pharmacy


Key facts

  • The new NICE guidance outlines a major shift in the management of type 2 diabetes from a glucose-centred approach to one that focuses equally on glucose, cardiovascular and renal risks
  • Most newly diagnosed adults should receive modified-release metformin and SGLT-2 inhibitor (e.g. dapagliflozin) as first-line therapy
  • Modified-release metformin replaces standard-release metformin to increase tolerability and adherence
  • SGLT-2 inhibitors can be prescribed at the same time as metformin to reduce the number of health professional appointments
  • SGLT-2 inhibitors will become much more widely used – advising on side-effects and safe use will be crucial
  • GLP-1 receptor agonists will be used earlier in specific groups e.g. SC semaglutide in those with atherosclerotic cardiovascular disease
  • Patients with chronic kidney disease should be prescribed medicines that are tailored to their kidney function
  • Patients with multiple comorbidities should be involved in decisions regarding which condition to prioritise when choosing medicines

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